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Family Solanaceae
Jerusalem cherry
Solanum pseudo-capsicum Linn.

Shan hu yin

Scientific names Common names
Solanum capsicastrum var. caaguazuense Chodat False capsicum (Engl.)
Solanum diflorum Vell. Jerusalem cherry (Engl.)
Solanum eremanthum Dunal Madeira winter cherry (Engl.)
Solanum hygrophilum Schltdl. Christmas cherry (Engl.)
Solanum ipecacuanha Chodat Coral bush (Engl.)
Solanum jaliscanum Greenm.  
Solanum mexiae Standl.  
Solanum plurifurcipilum Bitter  
Solanum pseudocapsicum Linn.  
Solanum tucumanense Griseb.  
Solanum ulmoides Dunal  
Solanum validum Rusby  
Solanum pseudocapsicum L. is an accepted name.  The Plant List

Other vernacular names
AFRIKAANS: Jerusalemkersie.
CHINESE: Shan hu yin.
GERMAN: Falsche Jerusalemkirsche, Korallenstrauch.
SWEDISH: Korallbär.

Jerusalem cherry is an erect, branched and non-spiny shrub growing to a height of one meter. Leaves are alternate, oblong to lanceolate, up to 10 centimeters long, wavy, glossy green above. Flowers are nodal, white and solitary. Fruit is globose, yellow or reddish, up to 1 centimeter in diameter.

- Ornamental cultivation in Philippines.
- Common in commercial botanical garden in Baguio.


- GC-MS study of root for volatile components
yielded 41 compounds, representing 50% of the oil. Major components were fatty acids (26.8%), terpenoids (7.6%), and aldehydes (5.3%). Dominant compounds were hexadecanoic acid (24.1%), 2-methoxy-3-isopropylpyrazine (2.8%), and 15-methylhexadecanoic acid (2.1%). Other notable components were ß-elemene and δ-elemene. (6)
- Phytochemical studies have yielded alkaloids, glycosides, tannins and flavonoids.
- Berries contain substantial amounts of phosphorus and nitrogen.

- Analysis of berries yielded 25 components, constituting 99.8% of extract composition. The major components were alkaloids (38.55%), hydrocarbons (22.18%), fatty acid (19.38%), alcohol (13.27%), and carboxylic derivatives (3.73%). Mineral nutrient analysis yielded substantial amounts of phosphorus and nitrogen.
- Study of essential oil of unripe berries yielded twenty-one compounds, constituting 69.24% of total oil components. Major compounds were homologous series of alkanes, alcohol, aldehyde and terpenoids. The dominant components were decane (41.06%), undecane (29.26%), monoterpenoids (14.79%), sesquiterpene (3.21%) and a diterpene phytol (5.94%). (12)

- Alkaloids identified in S. pseudocapsicum are solanocapsine; solacasine; solateinemine; 2-fluoro-2',4,5 benzenethanamine; hexatriacontane; 3-ethoxyamphetamine; 2,2,2-trichloroacetamide; O-methylsolanocapsine; episolacapine; and isosolacapine. (16)
- GCMS analysis of hexane extractable fraction of leaves of S. pseudocapsicum yielded 35 compounds, of which 26 were identified accounting for 40-81% of the composition. Fraction 1 (F1) was dominated by alkanes (74.8%) with decane (44.1%), undecane (24.6%) and nonane (6.1%) as main constituents. F2 was dominated by alkanes, decane, undecane, tetradecane, and hexadecane. F3 showed a high proportion of nonane, terpenes, ketones, and an alcohol. F4 showed a high proportion o

f terpenes. dominated by acyclic diterpene phytol (35.8%). The presence of diterpene phytol in fraction 4 was reported to be toxic and lethal and reported to activate the peroxisome proliferator=activated receptor α (PPARα) and regulates gene expression involved in lipid metabolism in PPARα-expressing HepG2 hepatocytes. (19)

- All parts of the plant are considered poisonous, especially unripe fruits.
- Antimicrobial, antiviral, antispasmodic, antihypertensive, antioxidant and hepatoprotective.

Caution / Toxicity concerns
- Poison / Solanocapsine: Considered a poisonous plant. The poisonous ingredient has reported as solanocapsine, found throughout the Jerusalem cherry plant, but especially in the unripened fruit and leaves. Symptoms of poisoning include altered mental status, coma, delirium, diarrhea, drowsiness, dilated pupils, hallucinations, headache, low blood pressure, slow breathing, slow pulse, salivation, stomach pains, and vomiting. (13)
- Studies have implicated the berries in causing central anticholinergic syndrome characterized by thought impairment, recent memory disturbance, hallucinations, hyperpyrexia, ataxia, drowsiness, tachycardia, coma among others. Extract studies were predominated by alkaloids (38.55%). Other plant components detected were aramines, phentamins, dopamine, fluoxotine and amphetamine derivatives – potent psychostimulant in humans. Many of the compounds have pharmacological and toxicological importance in humans and the berries present of source of raw materials for drug development. (Research Paper)

Parts used
Bark, fruit, leaves and seeds.

- No reported medicinal use in the Philippines.
- In India, used in homeopathy medicine to treat acute lower abdominal pain and somnolence.
- In South Africa, reported topical use for treatment of boils and gonorrhea; orally, as a male tonic and for abdominal pain.
- In the Newar community of Pharping village in Kathmandu, Nepal, reported use of raw fruit for diabetes. (17)

Cytotoxicity / O-methylsolanocapsine / Leaves:
Study evaluated the in vitro cytotoxic properties of O-methylsolanocapsine isolated from Solanum pseudocapsicum leaves. Several steroidal alkaloids including solanocapsine, solacasine, solacapine, episolacapine, isosolacapine, and O-methylsolanocapsine were isolated from the arboreal part of the plants. Study confirmed O-methylsolanocapsine is more cytotoxic to the HeLa cell lines. Results indicate the steroidal alkaloids possess strong cytotoxic and antitumor properties. (1)
Antioxidant / Leaves:
Study evaluated various extracts of S. pseudocapsicum leaves for in vitro antioxidant activity. A crude methanolic extract showed potent antioxidant activity with IC50s of 49.57 ± 0.15 and 79.00 ± 0.08 mg/ml on DPPH and nitric oxide assays, respectively. The extracts exhibited no activity in the scavenging of hydroxyl or superoxide radicals. Also, none of the extracts were more active than standards (ascorbic acid and rutin). (2)
Antitumor / Leaves:
Antitumor activity of total alkaloid fraction of solanum pseudocapsicum leaves was tested against Dalton's Lymphoma Ascites model in mice and revealed increase in mean survival time and life span of tumor-bearing mice. The observed activity may be due to its cytotoxic properties. (4)
Study on leaf extracts has isolated 0-methylsolanocapsine with in vitro cytotoxic properties against some cancerous cell lines and merits in vivo studies to confirm its antitumor activity.
Solacasine / Antibacterial:
Systematic fractionation of alcohol extracts showed solacasine, a new steroidal alkaloid, to be the main antibacterial constituent. (3)
Alkaloid fraction of the methanol extract of Solanum pseudocapsicum was tested for hepatoprotective activity against CCl4 induced toxicity in rat hepatocytes and showed antihepatotoxic effect at very low concentrations and suggests further studies of the alkaloid fraction to identify the active principles. (5)
Volatile Compounds / Roots:
Hydrodistillation yielded 41 compounds (50% of the oil) from the roots of Solanum pseudocapsicum. The dominant compounds were hexadecanoic acid (24.1%), 2-methoxy-3-isopropylpyrazine (2.8%) and 15-methylhexadecanoic acid (2.1%). The high proportion of the fatty acids was considered to be contributory to its medicinal properties. (6)
Antioxidant: Of the six extracts of SP tested for antioxidant activity, the crude methanolic extract showed potent antioxidant activity. The extract also showed potent scavenging activity against ABTS free radical, however, in a degree less than the standards used. (7)

Cytotoxic Activity of Alkaloids: All five alkaloid fractions of the methanolic extracts of leaves, ripe fruits, roots, seeds and stems of SP showed potent cytotoxic activity with the HT-29 cell line showing the most sensitivity. The most potent was found in the fraction of leaves. (8)
Chemical and Nutrient Analysis of Berries: Analysis of berries yielded 25 components, constituting 99.8% of extract composition. Major components were dominated by alkaloids (38.55%), hydrocarbons (22.18%), fatty acids (19.38%), alcohols (13.27%) and the derivatives of carboxylic acid (3.73%). Mineral nutrient evaluation showed substantial amount of phosphorus and nitrogen. The presence of other components such as aramines, phentamines, dopamine, fluoxotine and amphetamines are noteworthy as these components can cause potent psychoactive stimulation in humans. (see constituents above) (0)
Antifungal / Leaves and Roots: Various extracts of leaves, fruits, and roots of S. pseudocapsicum were investigated for antimycotic activities. Acetone and methanol extracts showed significant growth inhibition of Aspergillus niger and Penicillium notatum and marked suppression of growth of Fusarium oxysporum. Results suggest a potential application as a fungicide. (14)
• Antitumor Activity / Total Alkaloidal Fraction / Leaves: Study evaluated a total alkaloid fraction of methanolic extract of S. pseudocapsicum leaves for in-vivo antitumor activity against Dalton's Lymphoma Ascites model in mice.
Results showed antitumor activity at total alkaloid fraction dose of 2.5 and 5.0 mg/kbw as evidenced by increase in mean survival time and percentage increase in life span of tumor bearing mice. The antitumor activity may be due to its cytotoxic property. However, treatment also caused a significant decrease in body weight below normal indicating toxicity of the treatment. (17)


Updated October 2019 / July 2015

Photos © Godofredo Stuart / StuartXchange
OTHER IMAGE SOURCE: / Illustration / Solanum pseudocapsicum / A portfolio of illustrations of some plants known to be poisonous in S.F. Australia / © Australian Botanical Illustration

Additional Sources and Suggested Readings
In vitro cytotoxic properties of O-methylsolanocapsine isolated from Solanum pseudocapsicum leaves
/ Santoshkumar H. Dongre et al / Indian Journal of Pharmacology / Vol. 39, No. 4, July-August, 2007, pp. 208-209


In vitro antioxidant properties of Solanum pseudocapsicum leaf extracts.


Solacasine, a new steroidal alkaloid fromSolanum pseudocapsicum possessing antimicrobial activity / Cellular and Molecular Life Sciences / L. A. Mitscher et al / DOI 10.1007/BF01920766

Anti√©© activity of total alkaloid fraction of solanum pseudocapsicum leaves /
Shrishailappa Badami et al / Phytotherapy Research / Volume 17 Issue 9, Pages 1001 - 1004
Hepatoprotective Effect of the Total Alkaloid Fraction of Solanum pseudocapsicum Leaves / P. Vijayan, H.C. Prashanth et al / Summary Pharmaceutical Biology 2003, Vol. 41, No. 6, Pages 443-448 / DOI 10.1076/phbi.41.6.443.17827
Volatile Components from the Roots of Solanum pseudocapsicum / A.A. Aliero, O.T. Asekun, D.S. Grierson, A.J. Afolayan. / Journal of Medicinal Food, September 2007, 10(3): pp 557-558. / doi:10.1089/jmf.2006.230.
In vitro antioxidant properties of Solanum pseudocapsicum leaf extracts / S Badami, Om Prakash, SH Dongre, B Suresh / RESEARCH LETTER, 2005; 37(4): pp 251-252
The Cytotoxic Activity of the Total Alkaloids Isolated from Different Parts of Solanum pseudocapsicum / Pottekkad Vijayan et al / Biological & Pharmaceutical Bulletin Vol. 27 (2004) , No. 4 528
Chemical and nutrient characterization of Solanum pseudocapsicum berries / A. A. Aliero, D. S. Grierson and A. J. Afolayan / African Journal of Biotechnology, November 2005; Vol. 4 (11): pp 1300-1303
Solanum pseudocapsicum L. / Synonyms / The Plant List
Chemical Composition of the Essential Oil from Solanum pseudocapsicum / A.A. Aliero, D.S. Grierson and A.J. Afolayan / Pakistan Journal of Biological Sciences, 9: 1175-1177 / DOI: 10.3923/pjbs.2006.1175.1177
Jerusalem Cherry Poisoning / Health Guide / New York Times
Antifungal Activity of Solanum pseudocapsicum / A.A. Aliero, D.S. Grierson and A.J. Afolaya / Research Journal of Botany, 1: pp 129-133 / DOI: 10.3923/rjb.2006.129.133
Solanum pseudocapsicum / Common names / USDA Taxonomy for Plants
Solanum Alkaloids and their Pharmaceutical roles: A Review / Jayakumar K, Murugan K / Journal of Analytical & Pharmaceutical Research, 3(6) / DOI: 10.15406/japlr.2016.03.00075
Antitumor activity of total alkaloid fraction of Solanum pseudocapsicum leaves / Shrishailappa Badami, S A Manohara Reddy, E P Kumar, P Vijayam, B Suresh / Phytotherapy Reserarch, Nov 2003; 17(9): pp 1001-1004 /

Chemical Composition of the Hexane Extract from the Leaves of Solanum pseudocapsicum / A A Aliero, O T Asekun, D S Grierson and A J Afolayan / Asian Journal of Plant Sciences, 2006; 5(6): pp 1054-1056

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